Projects Funded

The Saving tiny Hearts Society’s mission is to raise seed money for grossly under-funded, lifesaving grass roots research of congenital heart defects (CHD's). This seed funding acts as a bridge for this research to millions of dollars of extramural funding from the National Institute of Health (NIH) or other outside funding. To date, the StHS has funded the following projects:

• Defining New Mechanisms to Uncover the Early Developmental Manifestations of Arrhythmogenic Cardiomyopathy in Children
  Principle Investigator – Farah Sheikh
  The Regents of the University of California
  University of California San Diego
• Engaging Sonographers to Improve Prenatal Screening for Heart Defects in Practice
  Principle Investigator – Nelangi M. Pinto
  University of Utah
• Augmenting O-GlcNAcylation, an Intrinsic Cardiovascular Stress Adaption, to Prevent Low Cardiac Output Syndrome in Mocel of Pediatric Cardiac Surgery
  Principle Investigator – Aaron Olson
  Seattle Children's Hospital
• Myosin Heavy Chain 7 Mutation and Hypertrophic Cardiomyopathy
  Principle Investigator – Charles E. Murray
  University of Washington
• Defining New Paradigms for Arrhythmia and Sudden Cardiac Death in Children
  Principle Investigator – Peter Mohler, PhD
  The Ohio State University, Columbus, Ohio
  Second Year Funding

• Defining New Paradigms for Arrhythmia and Sudden Cardiac Death in Children
  Principal Investigators – Peter Mohler, PhD
  The Ohio State University, Columbus, Ohio
• Pulmonary Venous Obstruction in Congenital Heart Disease
  Principal Investigators – Chris Caldarone, MD, FRCSC
  The Hospital for Sick Children, Toronto, Canada
• An International Collaboration to Create a Brain MRI Atlas for Infants with Congenital Heart Defects
  Principal Investigators – Daniel J. Licht, MD and James Gee, MD
  Children's Hospital of Philadelphia, Philadephia, Pennsylvanian

• Mechanisms in the Pathogenesis of HLHS
  Principal Investigator – Dr. Pirooz Eghtesady
  Washington University
• Fetal and Postnatal Effects of Hypoxia on Neuro Outcome in Congenital Heart Disease
  Principal Investigators – Richard A. Jonas, MD and Mary T. Donofrio, MD
  Children's National Medical Center
• Unbalanced Atrioventricular Septal Defect: A CHSS Inception Cohort Study
  Principal Investigator – David M. Overman, MD
  Children's Hospital & Clinics of Minnesota
• 3-D Cardiac Tissue Engineering: Using Decellularized Scaffolds For Engineering Whole Heart
  Principal Investigator – Sunjay Kaushal, MD, PHD
  Children's Memorial Hospital, Chicago
  Second Year Funding

2009-2010 Grant Awards ($100,00):

• 3-D Cardiac Tissue Engineering: Using Decellularized Scaffolds For Engineering Whole Heart
  Principal Investigator – Sunjay Kaushal, MD, PHD
  Children's Memorial Hospital, Chicago

• Myocardial Protection and Support in Cyanotic Congenital Heart Disease
  Principal Investigator – Henry Michael Spotnitz, MD
  Columbia University